3DM Engineering

Game-changing efficiency for protein design projects

Enhance every step: from protein selection to final optimizations

Cut down on labor-intensive screening or extensive rounds of testing by quickly identifying promising starter proteins and strategically introducing functional diversity. Whether you are still choosing a target or ready to optimize your protein, 3DM Engineering supports all steps of the in-silico engineering pipeline with customizable entry points and seamless end-to-end progression.

Optimally sample the sequence space

Leverage a vast repository for confident choices

With an extensive database of protein families and associated data, you can quickly and reliably identify the most promising protein candidates to kickstart your project. This comprehensive resource ensures informed decisions when selecting starter proteins.

Smart hotspot selection

Target the right mutations for functional diversity

Combine your domain knowledge with our analytics and advanced predictive algorithms to identify key hotspots for introducing functional diversity into protein sequences. This targeted approach increases efficiency and success rate of your engineering projects.

AI-driven protein optimization

Improve variants with advanced machine learning

Build on initial variants and iteratively refine your protein to meet specific requirements using advanced AI-based variant predictors. Our technology consistently outperforms competitors in achieving optimized protein variants. Leveraging a vast repository of protein family data, our system introduces functional diversity to ensure superior results.

Integrated IP navigation

Ensure commercial viability with patent awareness

Keep on top of your freedom-to-operate throughout the protein engineering process with 3DM’s integrated intellectual property analysis. Evaluate the IP landscape and be aware of any sequence space restrictions and opportunities.

Intuitive and user-friendly tools

Enjoy a hassle-free experience

The user-friendly web application offers structure-based sequence alignments and mutation effect visualization. This robust interface makes it easier to navigate the complex data and streamline your protein engineering workflow.

3DM Discovery
Screen proteins quicker for target discovery and drug design
3DM Antibodies
Accelerate antibody development with sequence property insights
Helix Pathogenicity
Predict missense variant pathogenicity with unmatched precision